Cardiac Injury Linked to Increased Mortality in COVID-19
HealthDay News – Heart injury is linked to increased mortality among hospitalized patients with Coronavirus Disease 2019 (COVID-19), according to a study published online March 25 in JAMA Cardiology.
Shaobo Shi, MD of Renmin Hospital, Wuhan University in China, and colleagues examined the association between heart injury and mortality in a cohort study conducted from January 20, 2020 to February 10, 2020. The final analysis included 416 hospitalized patients with COVID-19.
The researchers found that common symptoms were fever, cough, and shortness of breath (80.3, 34.6 and 28.1 percent, respectively). A total of 82 patients had a heart injury; These patients were older, had more comorbidities, and had higher white blood cell counts than patients without heart damage. They also had a higher percentage of multiple mottling and frosted glass opacity in radiological findings (64.6 versus 4.5 percent). Compared to patients without heart injury, a greater proportion of patients with heart injury required non-invasive mechanical ventilation (3.9 versus 46.3 percent) or invasive mechanical ventilation (4.2 versus 22 percent). Patients with heart injury had more complications and higher mortality rates than those without heart injury (51.2 versus 4.5 percent). The risk of death in patients with or without heart injury was increased from symptom onset and from admission to endpoint (hazard ratios, 4.26 and 3.41, respectively).
“Although the exact mechanism of heart injury needs further investigation, the results presented here underscore the need to consider this complication when treating COVID-19,” the authors write.
Abstract / full text
Cardiology COVID19 Medicine